NIH Parent STTR Grant (R41/R42) Clinical Trial Optional
The NIH Small Business Technology Transfer (STTR) program (R41/R42) is a congressionally mandated program that reserves a percentage of the extramural research budget for small businesses to work cooperatively with research institutions. This 'parent' announcement is for clinical trial optional projects, supporting early-stage research and development of innovative technologies.
Deadline
Rolling
Est. Time
3-6 months for proposal preparation and registration
Source
SBIR/STTR
Eligibility Requirements
Small business concerns (SBCs) that meet NIH definition (organized for profit, located in U.S., >50% U.S.-owned by individuals/corporations, 500 or fewer employees) and have a formal cooperative research agreement with a US research institution (university, non-profit hospital, etc.).
Who Can Apply
For-profit small businesses collaborating with a non-profit research institution.
Application Instructions
Applications must be submitted via Grants.gov using the specific Parent FOA announcement number (e.g., PA-24-239) and standard NIH SF424 (R&R) application forms.
Required Documents
- Research Plan
- Specific Aims
- Budget
- Biographical Sketches
- Letters of Support
- Small Business Concern Documentation
- Institutional Commitment Letter
Geographic Restrictions
United States
Required Essays
- Specific Aims
- Research Strategy
- Human Subjects Protection (if applicable)
How to Stand Out
Focus on the innovative nature of the technology and ensure the partnership between the small business and the research institution is balanced and clearly defined in the Research Plan.
Risk Warnings
Requires strict adherence to NIH human subjects policies if clinical trials are included. Compliance with rigorous federal reporting standards is mandatory.