NIH Small Business Innovation Research (SBIR) Parent Grant (Clinical Trial Optional)
The NIH Small Business Innovation Research (SBIR) program is a congressionally mandated set-aside program for small businesses to engage in Federal Research/Research and Development (R/R&D) with the potential for commercialization.
Deadline
Rolling
Est. Time
3-6 months for preparation and submission
Source
SBIR/STTR
Eligibility Requirements
Small business concerns (SBCs) that are American-owned and independently operated, for-profit, with 500 or fewer employees.
Who Can Apply
Small businesses that meet the NIH size and ownership requirements as defined in the official Omnibus Solicitation.
Application Instructions
Applicants must register with SAM.gov, Grants.gov, and the eRA Commons before applying. Applications must be submitted through the appropriate NIH Parent Announcement via Grants.gov.
Required Documents
- SF424 (R&R) Form
- Research Strategy
- Budget Justification
- Project Summary/Abstract
- Specific Aims
- Biographical Sketches
Geographic Restrictions
United States
Required Essays
- Research Strategy
- Commercialization Plan
How to Stand Out
Align your research focus closely with specific NIH Institute or Center (IC) priorities; ensure the commercialization plan is robust and demonstrates a clear path to market.
Risk Warnings
The application process is highly competitive and rigorous. Failure to follow complex formatting guidelines or missing registration deadlines will result in immediate rejection.